2013年10月10日

施打hCG當天E2太高應考慮囊胚植入以讓子宮內膜修復

施打hCG當天,
P4較低(<1.5),懷孕率較高
LH較低(<1.8),懷孕率較高
E2太高(>3900),懷孕率較低

E2太高,應考慮Day5囊胚期胚胎植入以讓子宮內膜修復

http://humrep.oxfordjournals.org/content/24/11/2902.full


Table IV
Comparison between different parameters for pregnant and non-pregnant women in high responders group (E2> 2446 pg/ml)
Pregnant (n = 15)Not pregnant (n = 36)P
Age (years)32.5 (4.5)32.3 (3.9)0.90
BMI (kg/m2)23.3 (3.3)23.5 (3.3)0.90
No. of trials1 (0.2)1.1 (0.4)0.54
Cause of infertility (%)0.15
 Male53.366.7
 Ovulatory6.72.8
 Tubal013.9
 Idiopathic4016.7
 Lesbian00
Treatment (%)0.06
 IVF33.311,1
 ICSI66.788.9
Stimulation
 Duration of stimulation (days)10 (1.7)9.6 (1.3)0.46
 Total FSH administered (IU)2000 (354)1933 (262)0.46
 Duration of antagonist treatment (days)6 (1.7)5.5 (1.2)0.34
 Basal FSH (IU/l)6.1 (1.6)7.2 (2.1)0.07
 Basal E2 (pg/ml)42.6 (15)39.4 (10.2)0.38
 E2 on Day 6 (pg/ml)829.5 (326.8)987.1 (420.5)0.20
 E2 on Day 8 (pg/ml)1769.1 (887)1941 (833)0.55
 E2 on hCG day (pg/ml)3220.3 (636)3933 (1209)0.01
 LH on day of hCG (IU/L)1.2 (0.7)2.1 (1.9)0.02
 Progesterone on day of hCG (ng/mL)1.1 (0.4)1.5 (0.4)0.01
 FSH on hCG day (IU/l)12.9 (3.5)13.7 (3.9)0.48
Treatment outcome
 No. COCs retrieved16.6 (6.8)17.5 (8.5)0.71
 No. embryos transferred1.6 (0.5)1.7 (0.4)0.79
 Quality score of transferred embryos4.2 (1.6)4 (1.4)0.7
  • Values are means (standard deviation).

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