2015年5月16日

施打hCG於COH末期,造成FSH & LH 下降

施打hCG於COH末期,造成FSH & LH 下降
施打hCG於COH末期, 懷孕率高於傳統COH(37  vs  29%)
施打hCG於COH末期, rFHS 劑量低於傳統COH(1273 vs 1617iu)

http://humrep.oxfordjournals.org/content/24/11/2910.full




Table IV
Serum hormone levels on last day of stimulation before final oocyte maturation*
rFSH standard treatment group** mean (SD)Low-dose hCG treatment group** mean (SD)Between-group difference (95% CI)P-value for between-group difference***
FSH (IU/l)14.6 (3.3)8.2 (4.2)−6.4 (−8.4 to −4.5)<0.001
LH (IU/l)2.5 (4.3)1.4 (1.4)−1.1 (−2.8 to 0.6)0.20
E2 (pg/ml)2044 (1204)2250 (1739)206 (−555 to 966)0.59
Progesterone (ng/ml)1.2 (0.4)1.1 (0.8)−0.1 (−0.4 to 0.2)0.54
hCG (IU/l)0.1 (0)8.8 (10)8.7 (5.2–12.2)<0.001
  • *All calculations have been carried out to full arithmetic precision, but results are shown as rounded values. Absolute between-group difference = (Low-dose hCG group value [third column]) − (rFSH group value [second column]). A negative value in the fourth column favours Low-dose hCG.
  • **Mean values per patient (SD).
  • ***P-values for t-test for independent samples; significant P-values <0.05 are bold

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