試管嬰兒病患誘導排卵反應不佳之高齡病患可考慮使用DHEA增加懷孕率及活產率
但DHEA並無法增加E2值及卵泡數量
http://humrep.oxfordjournals.org/content/25/10/2496.long
Table IV
Comparison between the two groups for both treatment cycles.
| Variables | DHEA (n= 26) | Control (n = 25) | P-value |
|---|---|---|---|
| Mean E2a on hCG (pg/ml) | 732 ± 337 | 917 ± 487 | 0.2 |
| Mean E2 per retrieved oocyte (pg/ml) | 239 ± 120 | 335 ± 150 | 0.35 |
| Mean progesterone on hCG (ng/ml) | 0.8 ± 0.6 | 0.7 ± 0.4 | 0.71 |
| Endometrial thickness on hCG (mm) | 10.5 ± 2.5 | 10.8 ± 2.8 | 0.74 |
| Mean number of retrieved oocytes | 3.2 ± 1.6 | 3.5 ± 2.4 | 0.65 |
| Fertilization rate (%) | 58.20% | 56.30% | 0.42 |
| Mean no. of embryo transfer | 2.1 ± 1.0 | 2.2 ± 0.7 | 0.73 |
| Mean scoring of leading embryo transfer | 3.1 ± 0.5 | 3.3 ± 0.4 | 0.42 |
| Clinical Pregnancy (%) | 7 (26.9%) | 3 (12.0%) | 0.07 |
| Live birth rate | 6 (23.1%) | 1 (4.0%) | 0.05 |