以time-lapse培養系統觀察胚胎孵化之方式,
發現不同受孕方式(IVF 或 ICSI)會影響囊胚期胚胎孵化之方式
ICSI好發生
type 1 孵化
IVF 好發生
type 2 孵化
Type 1 was characterized by penetration of the zona pellucida (ZP) by small trophectoderm projections,
type 2 was preceded by a regular rupture of the ZP followed by extrusion of the blastocyst.
http://www.ncbi.nlm.nih.gov/pubmed/23909991