施打hCG當天E2大於3000要小心OHSS

施打hCG當天E2>3000要小心卵巢過度刺激OHSS

http://humrep.oxfordjournals.org/content/18/6/1140.full

Prediction of ovarian hyperstimulation syndrome (OHSS)

Estradiol level has an important role in the prediction of OHSS

1. Mohamed Aboulghar1

+Author Affiliations

1. Department of Obstetrics and Gynecology, Cairo University and the Egyptian IVF‐ET Center, Maadi, Cairo, Egypt

1. 1To whom correspondence should be addressed at: 3, street no. 161 Hadayek El Maadi, Maadi, Cairo 11431 Egypt. e‐mail: ghar@link.net

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Abstract

The cascade of events that leads to the development of ovarian hyperstimulation syndrome (OHSS) is almost always accompanied by elevated estradiol (E₂) levels. The role of estrogen level in OHSS has not been confirmed; however, it was shown repeatedly in the literature that elevated levels of E₂ constitute a risk for OHSS. Monitoring E₂ was found to be effective in reducing the incidence of OHSS. It was also reported that reducing the E₂ level by coasting helps to prevent OHSS. It is believed that irrespective of the debatable role of estrogen in the pathogenesis of OHSS, there is a general agreement that E₂ assay is an important marker to detect the majority of patients at risk of OHSS.