捐卵數量需4個以上成熟卵子才可達到適當懷孕率

捐卵受卵IVF療程，至少需4個以上成熟卵子才可達到不錯懷孕率

http://www.ncbi.nlm.nih.gov/pubmed/21088879

J Assist Reprod Genet. 2011 Mar;28(3):263-7. doi: 10.1007/s10815-010-9511-7. Epub 2010 Nov 19.

A shared egg donor program: which is the minimum number of oocytes to be allocated?

Abstract

PURPOSE:

To evaluate which is the minimum number of oocytes to be allocated to each recipient in a shared egg donor program.

METHODS:

We analyzed 953 recipients that received at least 4 metaphase II (MII) oocytes in the period 2006-2008. We retrospectively divided the recipients according to the number of MII oocytes actually received.

RESULTS:

No statistically significant differences were found among the analyzed strata in clinical pregnancy rate (A:43.7%; B:45.6%; C:48.6%; D:45.5%; E:53%, P=NS) and miscarriage rate. However, the rate of top quality transferred embryos, and the embryo freezing rate were significantly higher among those recipients that received 7 or more mature eggs.

CONCLUSIONS:

After a large sample was analyzed, no significant differences in fresh embryo transfer outcome were encountered when a different number of oocytes was allocated. A minimum of 4 MII oocytes seems to achieve satisfactory pregnancy rates in our shared egg donor program.