P4過高對於囊胚期植入較無明顯影響

P4>1.5 ng/ml對於囊胚期植入較無明顯影響



http://www.ncbi.nlm.nih.gov/pubmed/17555751?dopt=Abstract

Fertil Steril. 2009 Mar;91(3):949-52. Epub 2007 Jun 6.

Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer.

Papanikolaou EG1, Kolibianakis EM, Pozzobon C, Tank P, Tournaye H, Bourgain C, Van Steirteghem A, Devroey P.

Author information

Abstract

Four hundred eighty-two patients undergoing single ET with GnRH-antagonist/recFSH protocol were analyzed. The incidence of premature luteinization (P above 1.5 ng/mL on the day of hCG administration) was 18.2%. Even modest rises of P in the follicular phase have detrimental effect on the implantation potential of a good-quality cleavage stage embryo. On the contrary, premature luteinization in the blastocyst subgroup had no effect on the pregnancy outcome.