Data adapted and interpreted from
Hargreave and Elton (1983) who studied
in vivo conception in 867 subfertile couples. Note the effective plateau in conception rates with higher concentrations of motile cells and reduced per cent conception below ∼2 million motile cells/ml (blue bar). Importantly, small changes in the concentration of motile cells, e.g. from 0.5 to 1 million/ml, can have a noticeable effect on the chances of conception. This is the zone where small changes in the proportion of motile cells, for example, with
in vitro drug stimulation can have a noticeable effect on fertility. These data are consistent with many other studies in the literature.
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