2013年6月20日

玻璃化冷凍懷孕率達36%

胚胎玻璃化冷凍優於慢速冷凍
懷孕率達36%,類似新鮮胚胎懷孕率

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463664/

Table 3

Assisted reproduction outcomes of fresh cycles, slow freezing and vitrification
ParametersFresh cycleSlow freezingVitrificationP-value (Fresh vs. Slow)P-value (Fresh vs. Vitrification)P-value (Slow vs. Vitrification)
General clinical data
 Embryos Transferred2.2 ± 0.92.9 ± 0.902.6 ± 0.70.070.230.45
 Implantation rate (%)298/1448(20.6)48/334(14.4)142/719(19.8)0.010α’0.6510.035
 Clinical pregnancy rate (%)239/657(36.4)39/151(25.8)109/300(36.3)0.014α’0.9890.025
Multiple pregnancy rate(%)58/657(8.8)9/151(6.029/300(9.7)0.2490.6750.181
Live birth (LB) rate (%)225/657(34.3)35/151(23.2)106/300(35.3)0.009α’0.7430.009α’
Loss of pregnancy
 Early abortion rate(%)23/239(9.6)3/39(7.7)18/109(16.5)0.7010.0640.175
 Late abortion rate(%)15/239(6.3)3/39(7.7)2/109(1.8)0.7390.0750.082
 Induced abortion rate(%)2/239(0.8)1/39(2.6)00.8951.0000.264
 Ectopic pregnancy rate(%)9/239(3.8)04/109(3.7)0.6191.0000.573
Mode of delivery
 Spontaneous vaginal delivery rate(%)34/190(17.9)5/32(15.6)6/85(7.1)0.7550.0190.157

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