LH對於P4 level 無明顯影響

COH過程中補充LH對於P4 level 無明顯影響

hCG所含LH為rLH之7倍強

LH對P4形成及代謝影響相當複雜

http://humrep.oxfordjournals.org/content/27/1/232.full

Figure 1

Effects of LH on progesterone production during the follicular phase. Left part: LH acting on theca cells via constitutive receptors present during the whole follicular phase has a dual effect on progesterone synthesis. Stimulation of 3β HSD type II induces a positive effect on progesterone production. Activation of CYP 17 which converts progesterone and pregnenolone to 17 OH derivates reduces progesterone synthesis. The overall effect depends on the respective activation of these two enzymatic activities Right part: LH acts on granulosa cells via receptors present only during the late follicular phase. LH activates 3β HSD type II enzymatic activity with a positive effect on progesterone production. 3β HSD II: 3 beta hydroxysteroid deshydrogenase type II CYP 17: Cytochrome P450 17 α-hydroxylase.