子宮內膜異位對於基礎濾泡及優勢卵子數量並無顯著減少作用

1. 比較患有子宮內膜異位及未 患有 子宮內膜異位之卵巢卵子數量
2. 研究顯示子宮內膜異位對於基礎濾泡及優勢卵子數量並無顯著減少作用
3. 此結論暗示對於併有子宮內膜異位之不孕症病患，採用手術摘除治療應更保守謹慎


Fertil Steril. 2011 Feb;95(2):525-7. Epub 2010 Apr 7.

Effects of ovarian endometrioma on the number of oocytes retrieved for in vitro fertilization.

Almog B, Shehata F, Sheizaf B, Tan SL, Tulandi T.

Source

Department of Obstetrics and Gynecology, McGill Reproductive Center, McGill University Health Center, Montreal, Quebec, Canada.

Abstract

OBJECTIVE:

To evaluate the effects of ovarian endometrioma on the number of oocytes retrieved for IVF.

DESIGN:

Retrospective case control study.

SETTING:

University-based tertiary medical center.

PATIENT(S):

We studied 81 women with unilateral endometrioma who underwent their first IVF cycle.

INTERVENTION(S):

Oocyte collection.

MAIN OUTCOME MEASURE(S):

The numbers of antral follicles and the retrieved oocytes in the ovary that contained endometrioma were compared with those from the contralateral ovary. Antral follicle count and the total number of oocytes retrieved from these women then were compared with those in 162 age-matched women with no endometrioma or endometriosis, who also underwent the first IVF treatment cycle.

RESULT(S):

There was no significant difference in the number of antral follicles and oocytes retrieved in the endometrioma-containing ovary (6.0 ± 0.4 and 7.7 ± 1.0, respectively) and in the opposite ovary (6.1 ± 0.5 and 8.5 ± 0.9, respectively). There was no correlation between the size and the number of endometriomas with the number of retrieved oocytes. Antral follicle count and the number of retrieved oocytes in these women (15.0 ± 1.6 and 11.9 ± 0.8) were similar to those in women with no endometrioma (14.2 ± 1.4 and 11.4 ± 0.5, respectively).

CONCLUSION(S):

The presence of ovarian endometrioma in a controlled ovarian hyperstimulation cycle for IVF treatment is not associated with a reduced number of oocytes retrieved from the affected ovary.