使用IVF 新鮮胚胎或冷凍胚胎植入懷孕率高於ICSI懷孕率

對於精蟲品質較差之病患，使用IVF vs. ICSI施行試管結果顯示
使用IVF 新鮮胚胎或冷凍胚胎植入懷孕率及活產率(44.2% and 38.3%)高於ICSI植入懷孕率及活產率(40.9% and 31.9)

http://www.ncbi.nlm.nih.gov/pubmed/20420272

Clin Exp Obstet Gynecol. 2010;37(1):17-8.

Fertilization by intracytoplasmic sperm injection with sperm with subnormal morphology using strict criteria results in lower live delivered pregnancy rates following frozen embryo transfer rather than eggs fertilized conventionally.

Check JH, Dix E, Bollendorf A, Check D.

Source

The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com

Abstract

PURPOSE:

To determine if fertilization by intracytoplasmic sperm injection (ICSI) lowers pregnancy rates following frozen embryo transfer compared to conventional insemination similar to findings with fresh embryo transfer.

METHODS:

Clinical and live delivered pregnancy and implantation rates were compared according to whether the eggs were fertilized by conventional oocyte insemination vs ICSI over a 10-year period in women whose husbands had normal semen parameters except for having normal strict morphology between 2-5%.

RESULTS:

The clinical and live delivered pregnancy rates were 40.9% and 31.9, respectively, with ICSI vs. 44.2% and 38.3% for women having conventional insemination. The difference in live delivered pregnancy rates approached statistical significance.

CONCLUSIONS:

Choosing ICSI for subnormal morphology may not only possibly lower the chance of successful pregnancy following fresh embryo transfer but possibly also following frozen embryo transfer.