IVF或ICSI受孕胚胎分裂速度無統計差異

使用IVF或ICSI受孕胚胎之胚葉細胞分裂速度無統計差異

使用IVFI受孕胚胎之懷孕率似乎較ICSI受孕胚胎之懷孕率為高

http://www.ncbi.nlm.nih.gov/pubmed/21898104

Clin Exp Obstet Gynecol. 2010;37(3):183-4.

Effect of fertilization by intracytoplasmic sperm injection versus conventionalinsemination on embryo cleavage rates.

Check JH, Bollendorf A, Dix E, Katsoff D.

Source

The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com

Abstract

PURPOSE:

To determine if fertilization by conventional oocyte insemination vs intracytoplasmic sperm injection (ICSI) causes any difference in the maximum number of blastomeres of fresh or frozen thawed embryos transferred.

METHODS:

Retrospective evaluation of all in vitro fertilization (IVF) cycles over a 10-year period in cycles having a 2 embryos transferred where the semen analysis was normal except for strict morphology which was allowed to be 2-5% normal. The percentage of the maximum number of blastomeres in any transfers was compared according to the method of insemination.

RESULTS:

There were no differences in the maximum blastomere numbers in cycles where there was conventionalinsemination vs ICSI.

CONCLUSIONS:

Though higher pregnancy rates have been found following the transfer of embryos derived from conventional oocyte insemination vs ICSI, and higher pregnancy rates were found following single embryo day 3 transfers with embryos with more blastomeres, the beneficial effect of conventional insemination does not seem to be related to forming embryos with more rapid cleavage.