傳統選擇胚胎之方式影響到懷孕之早與晚，但不影響到整個療程之累計懷孕率

傳統選擇胚胎之方式不僅無法有效提高懷孕率，甚至下降懷孕率
冷凍保存所有胚胎似乎才是提高累計懷孕率之方法

傳統選擇胚胎可能影響到懷孕之早與晚，但不會影響到整個療程之累計懷孕率
Embryo selection techniques will not only be unable to improve live birth rates but also they could even lower the success rate of IVF. 

http://humrep.oxfordjournals.org/content/26/5/964.full

Embryo selection in IVF

1. Sebastiaan Mastenbroek1,*, 
2. Fulco van der Veen1, 
3. Abbas Aflatoonian2,
4. Bruce Shapiro3, 
5. Patrick Bossuyt4 and 
6. Sjoerd Repping1

+Author Affiliations

1. ¹Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
2. ²Research and Clinical Center for Infertility, Department of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Science, Yazd, Iran
3. ³Fertility Center of Las Vegas, University of Nevada School of Medicine, Las Vegas, NV, USA
4. ⁴Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

1. *↵Correspondence address. Tel: +31-20-5663090; E-mail:s.mastenbroek@amc.uva.nl

• Received February 11, 2010.
• Revision received January 23, 2011.
• Accepted February 4, 2011.

 

Next Section

Abstract

To optimize success rates of IVF, selection of the most viable embryo(s) for transfer has always been essential, as embryos that are cryopreserved are thought to have a reduced chance of implanting after thawing. Recent developments challenge this concept. Evidence is accumulating that all embryos can now be cryopreserved and transferred in subsequent cycles without impairing pregnancy rates or maybe even with an improvement in pregnancy rates. In such a scenario no selection method will ever lead to improved live birth rates, as, by definition, the live birth rate per stimulated IVF cycle can never be improved when all embryos are serially transferred. In fact, selection could then only lower the live birth rate after IVF. The only parameter that could possibly be improved by embryo selection would be time to pregnancy, if embryos with the highest implantation potential are transferred first.