ICSI懷孕嬰兒之畸形率可能略高於一般嬰兒

統計顯示，ICSI懷孕嬰兒之畸形率可能略高於一般嬰兒

http://humupd.oxfordjournals.org/content/13/6/515.full

Intracytoplasmic sperm injection (ICSI) in 2006: Evidence and Evolution

Table 6:

Chromosomal anomalies in 1586 ICSI fetuses (Bonduelle et al., 2002a)

Abnormal results	n	%	Confidence interval	% general populationa, b, c
De novo	25	1.6*	1.02–2.32	0.45–0.87
Sex chromosome	10	0.6*	0.30–1.16	0.19–0.27
Autosomal	15	0.9	0.53–1.56	0.26–0.60
Numerical	8	0.5	0.22–0.99	0.14–0.33
Structural	7	0.4%	0.18–0.91	0.11–0.22
Inherited	22	1.4*	0.87–2.09	0.47–.37
Total	47	3.0	2.19–3.92	0.92

• ^aJacobs et al. (1992) on 34 910 newborns.
• ^bFerguson-Smith and Yates (1984), on 52 965 prenatal samples.
• ^cHook (1981), Hook et al. (1984), Hook and Cross (1987) on prenatal samples.
• *Significant.