研究顯示植入後絕對臥床休息對懷孕率似乎無大助益
絕對臥床休息合併的焦慮心理壓力甚至還下降懷孕率
Hum Fertil (Camb). 2016 Apr;19(1):16-22. doi: 10.3109/14647273.2016.1148272. Epub 2016 Mar 17.
Bed rest following embryo transfer might negatively affect the outcome of IVF/ICSI: a systematic review and meta-analysis.
Abstract
The majority of patients undergoing in vitro fertilization (IVF) and intracytoplasmatic sperm injection (ICSI) treatment will reach the stage of embryo transfer (ET), but only a small proportion of transferred embryos implant. Bed rest following ET has been recommended as a way to prevent embryo expulsion by gravity. We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) published prior to May 2014 reporting the effect of bed rest following ET, and irrespective of language, country of origin, blinding or sample size. Four RCTs, including 757 women met the inclusion criteria. Bed rest following ET did not improve clinical pregnancy and live birth rates, but reduced the implantation rate. The quality of the trials included was moderate because of attrition bias and possible reporting bias. The findings of this systematic review and meta-analysis are concordant with previously published literature and suggest that bed rest is not beneficial following ET. Moreover, it might negatively affect the outcome of IVF/ICSI cycles via stress/anxiety mechanisms.
沒有留言:
張貼留言