50歲時AMH等於0

AMH由原始濾泡分泌
<25歲 AMH=3
25-35歲AMH=2-3
35-40歲AMH=1-2
40-50歲AMH=0-1
>50歲AMH=0

AMH與基礎濾泡於預測卵巢功能效果類似

http://humupd.oxfordjournals.org/content/16/2/113.full

Figure 1

AMH is secreted by pre-antral and antral follicles.

It seems to inhibit initial follicle recruitment and FSH-stimulated follicle growth. The role of AMH in the two main compartments of normal ovarian follicle development (the red centre represents the oocyte, the grey area represents the granulosa cell layer and the white area represents follicle fluid in the antrum). AMH is expressed in small and large pre-antral follicles (broken arrows) and in small antral follicles (whole arrow), and the latter mainly contributes to serum levels. Initial recruitment takes place as a continuous process, whereas cyclic recruitment is driven by a rise in FSH serum levels at the end of a previous menstrual cycle. The inhibitory effects of AMH are shown (a) on the initial recruitment of primary follicles from the resting primordial follicle pool and (b) on the sensitivity of antral follicles for FSH (reproduced with permission from Broekmans et al., 2008).

Figure 2

Left: Mean serum AMH levels show a reduction throughout reproductive life. Undetectable AMH levels after spontaneous menopause have been reported (constructed graphic). Right: Circulatory pattern of AMH during the menstrual cycle of young healthy women aged 18–24 years. Serum AMH levels have been shown to be stable throughout the menstrual cycle. Day 0 = day of LH surge (reproduced with permission from La Marca et al., 2006a).