已成功施行捐贈子宮之移植手術

目前已成功施行捐贈子宮之移植手術
將死亡捐贈者之子宮移植入先天無子宮之病患

http://www.ncbi.nlm.nih.gov/pubmed/23880349

Fertil Steril. 2013 Jul 20. pii: S0015-0282(13)00741-3. doi: 10.1016/j.fertnstert.2013.06.041. [Epub ahead of print]

Uterus transplantation from a deceased donor.

Akar ME, Ozkan O, Erdogan O, Ozkan O, Hadimioglu N.

Source

Department of Obstetrics and Gynecology, Akdeniz University, Antalya, Turkey. Electronic address: meakar@akdeniz.edu.tr.

Abstract

OBJECTIVE:

To demonstrate the technique for uterus retrieval and transplantation from a multiorgan donor.

DESIGN:

Video presentation of our case report. The video uses animation to demonstrate the technique. Institutional Review Board (IRB) approval was obtained.

SETTING:

University hospital.

PATIENT(S):

A 21-year-old woman with complete müllerian agenesis.

INTERVENTION(S):

Uterus allotransplantation has been performed from a deceased donor.

MAIN OUTCOME MEASURE(S):

Acquirement of cyclic menstrual function.

RESULT(S):

This video demonstrates the technique for uterus retrieval, perfusion, and transplantation. The recipient patient has been monitored regularly for vascular flow, immunosuppression, and infection control since the operation.

CONCLUSION(S):

Uterus transplantation requires extensive evaluation of the recipient and donor by an experienced multidisciplinary transplantation team both pre- and postoperatively. It has major risks related to surgery, immunosuppression, and pregnancy. Uterus transplantation might be considered promising only after the birth of a near-term healthy baby.

Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

KEYWORDS:

Uterus transplantation, deceased donor, uterine factor infertility