青春期15-19歲女性,確定有多囊性卵巢PCO之比例僅1%
遠低於成年女性
與肥胖有明顯相關
http://www.ncbi.nlm.nih.gov/pubmed/23756098
Fertil Steril. 2013 Aug;100(2):470-7. doi: 10.1016/j.fertnstert.2013.04.001. Epub 2013 Jun 5.
Prevalence of polycystic ovary syndrome in adolescents.
Source
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Abstract
OBJECTIVE:
To investigate the prevalence of polycystic ovary syndrome (PCOS) in adolescents and its association with obesity.
DESIGN:
Cross-sectional study using electronic medical records.
SETTING:
Not applicable.
PATIENT(S):
Adolescents aged 15-19 years (n = 137,502).
INTERVENTION(S):
None.
MAIN OUTCOME MEASURE(S):
PCOS diagnosed or defined according to National Institutes of Health (NIH) criteria.
RESULT(S):
The prevalence of a confirmed diagnosis of PCOS was 0.56%, which increased to 1.14% when undiagnosed cases with documented symptoms qualifying for PCOS according to NIH criteria were included. Compared with normal/underweight girls, the odds ratios (OR and 95% confidence interval [CI]) for confirmed PCOS diagnosis were 3.85 (3.04-4.88), 10.25 (8.16-12.84), and 23.10 (18.66-28.61) for overweight, moderately obese, and extremely obese adolescents, respectively, after adjusting for potential confounders. When adolescents with two or more supportive diagnoses were included (diagnosed and undiagnosed PCOS-NIH), the ORs (95% CI) for PCOS-NIH by weight class were significantly attenuated to 2.95 (2.53-3.44), 6.73 (5.78-7.83), and 14.65 (12.73-16.86) for overweight, moderately obese, and extremely obese adolescents, respectively.
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