http://informahealthcare.com/doi/abs/10.3109/09513590.2010.509829
Is pronuclear scoring a really good predictor for ICSI cycles?
October 2011, Vol. 27, No. 10 , Pages 742-747 (doi:10.3109/09513590.2010.509829)
Sevim Aydin1, Ozgur Cinar1, Berfu Demir1, Cem Korkmaz2, Ozlem Ozdegirmenci1, Serdar Dilbaz1, Umit Goktolga1
1Center for Assisted Reproductive Medicine and IVF, Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Ankara 06010, Turkey
2Center for Assisted Reproductive Medicine and IVF Gulhane Military Medical Faculty, Ankara 06010, Turkey
Background/Aims. Since the assessments of the morphology of oocytes, zygotes and/or embryos are of crucial importance to select the best candidate for pregnancy, many morphological evaluation tools have been proposed. Although embryo scoring, particularly cleavage and blastocyst stages, is more convincing due to successful results, zygote scoring still have a bias as different outcomes. In the current study, we designed a prospective study to test the reliability of zygote scoring by focusing on zygote evaluation techniques and its relation with embryo development and embryo selection for transfer.
Methods. A total of 1215 mature oocytes from 139 couples were evaluated for the study.Results. There is no correlation between published zygote scoring technique and embryo development.
Conclusions. We conclude that the inconsistency of data obtained from zygote scoring might be caused by the static nature of pronuclear stage embryos and thus pronuclear scoring seems to be unreliable evaluation technique for embryo selection.
Read More: http://informahealthcare.com/doi/abs/10.3109/09513590.2010.509829
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