Day 1胚胎植入懷孕率略低於Day 2-3胚胎植入

Day 1胚胎植入 vs Day 2-3胚胎植入
懷孕率 36 vs 42%

http://link.springer.com/article/10.1023%2FA%3A1020354318164

Journal of Assisted Reproduction and Genetics

October 2002, Volume 19, Issue 10, pp 456-461

Zygote Versus Embryo Transfer: A Prospective Randomized Multicenter Trial

Abstract

Purpose : To determine the efficiency of transferring human zygotes as opposed to human day 2 or 3 embryos.

Methods : A prospective, randomized, Multicenter trial. Patients were randomized into zygote or embryo transfer. Patients were prepared for oocyte retrieval using standardized protocols. Oocyte retrieval was performed under general anesthesia. Oocytes and spermatozoa were treated using standard laboratory techniques. All protocols were coordinated by the coordinating center.

Results : A total of 386 patients were included in the trial. Pregnancy rates were 36.5% after zygote transfer and 42% after embryo transfer. Implantation rates were equivalent (17%) in both groups.

Conclusions : No general difference was observed for zygote or embryo transfer. The results suggest that zygote transfer is a valid alternative to embryo transfer.