2003多囊性卵巢(PCO)診斷要點

2003年國際多囊性卵巢(PCO)診斷要點(criteria)
月經不規則
雄性賀爾蒙過高
超音波顯示多囊性卵泡(數量>12)
肥胖
胰島素抗性
LH上升

無單一criteria足以確認診斷PCO
PCO病人容易合併心藏血管疾病及第二型糖尿病

http://humrep.oxfordjournals.org/content/19/1/41.full

Revised 2003 consensus on diagnostic criteria and long‐term health risks related to polycystic ovary syndrome (PCOS)

1. The Rotterdam ESHRE/ASRM‐sponsored PCOS consensus workshop group

1. Correspondence to: Bart C.J.M.Fauser, Center of Reproductive Medicine, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands. e‐mail: b.fauser@erasmusmc.nl

• Received October 16, 2003.
• Accepted November 3, 2003.

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Abstract

Since the 1990 NIH‐sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome and, as such, no single diagnostic criterion (such as hyperandrogenism or PCO) is sufficient for clinical diagnosis. Its clinical manifestations may include: menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.

Table I.

Revised diagnostic criteria of PCOS

1999 criteria (both 1 and 2)

1. Chronic anovulation

2. Clinical and/or biochemical signs of hyperandrogenism, and exclusion of other aetiologies

Revised 2003 criteria (2 out of 3)

1. Oligo‐ and/or anovulation

2. Clinical and/or biochemical signs of hyperandrogenism

3. Polycystic ovaries

and exclusion of other aetiologies (congenital adrenal hyperplasias, androgen‐secreting tumours, Cushing’s syndrome)