MI卵子受孕後形成優良胚胎之比例亦較低
約50%MI卵子會在4h內成熟為MII卵子
MI卵子在3-6h內成熟&ICSI可達最佳結果
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325026/
In vitro matured MI oocytes | In vivo matured sibling oocytes (control) | |
Total N° of oocytes injected | 129 | 339 |
N° (%) of normal fertilized oocytesa | 67 (52)* | 229 (68) |
Embryo development on day 2 (%)b | ||
Excellent | 24* | 41 |
Good | 27 | 32 |
Poor | 49* | 27 |
Embryo development on day 3 (%)b | ||
Excellent | 22* | 38 |
Good | 28 | 32 |
Poor | 50* | 30 |
* Statistically different between columns (p < 0.05).
a Normal fertilized oocytes were defined as oocytes containing 2 pronuclei en 2 polar bodies.
b The proportions of excellent, good and poor embryos are expressed per total number of embryos obtained on day 2 or day 3.
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