2012年11月4日

MI卵子在3-6h內成熟&ICSI可達最佳結果

MI卵子成熟為MII卵子受孕率約52%
MI卵子受孕後形成優良胚胎之比例亦較低
約50%MI卵子會在4h內成熟為MII卵子
MI卵子在3-6h內成熟&ICSI可達最佳結果

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325026/


Comparison of fertilization and embryonic development between in vitro and in vivo matured sibling oocytes
In vitro matured MI oocytesIn vivo matured sibling oocytes (control)
Total N° of oocytes injected129339
N° (%) of normal fertilized oocytesa67 (52)*229 (68)
Embryo development on day 2 (%)b
Excellent24*41
Good2732
Poor49*27
Embryo development on day 3 (%)b
Excellent22*38
Good2832
Poor50*30
* Statistically different between columns (p < 0.05).
Normal fertilized oocytes were defined as oocytes containing 2 pronuclei en 2 polar bodies.
The proportions of excellent, good and poor embryos are expressed per total number of embryos obtained on day 2 or day 3.

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