卵細胞空泡或顆粒化會影響胚胎冷凍解凍懷孕率

卵子細胞質異常會影響日後胚胎冷凍解凍懷孕率

細胞質異常包括卵子細胞內空泡或顆粒化:

Group 3.1, with dark cytoplasm with slight granulation; 
Group 3.2, with vacuolar cytoplasm; 
Group 3.3, central granulation. Vacuolar cytoplasm and central granulation were regarded as severe cytoplasmic abnormalities,


細胞質以外之異常較不影響冷凍解凍懷孕率，包括
Group 2.1 with irregular shape; 
Group 2.2 with large perivitelline space; 
Group 2.3, dark zona pellucida; 

http://humrep.oxfordjournals.org/content/23/8/1778.full