http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582119/
J Assist Reprod Genet. 2008 Aug;25(8):427-30. doi: 10.1007/s10815-008-9247-9. Epub 2008 Sep 2.
Intrauterine insemination: is the timing correct?
Source
Department of Obstetrics & Gynecology, GATA School of Medicine, Ankara, Turkey. tansukucuk@gmail.com
Abstract
OBJECTIVE:
To evaluate the impact of follicle rupture on pregnancy rate in intrauterine insemination.
MATERIAL AND METHOD:
Retrospective cohort study. Evidence of follicle rupture was assessed by transvaginal ultrasonography following IUI. Two hundred ninety-six couples with unexplained infertility and 121 couples with male factor subfertility were included. Results of 578 cycles were analyzed here.
RESULT:
Clinical pregnancy rate was 23.5% (64/272) in the group when follicle rupture was evident by transvaginal ultrasonography, while it was only 8.8% (27/306) when follicle rupture was not evident (p < 0.001).
CONCLUSION:
Postponing IUI until observation of follicle rupture may yield a higher pregnancy rate.
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