2012年11月9日

MI胚胎須胚養2-4h後再施與ICSI

MI胚胎須胚養2-4h後再施與ICSI
直接於MI時期施與ICSI將導致較差之結果(胚胎受孕率:44 versus 28%)

http://humrep.oxfordjournals.org/content/19/7/1587.long
Table I.
Fertilization rate of MI, arrested IVM MI, rescued IVM MII and MII injected oocytes
MI ocytesArrested IVM MI oocytesRescued IVM MII oocytesMII oocytesP‐value
Injected oocytes (n)2491411164668
Degeneration (%)27 (11)115 (11)27 (6)187 (4)1,2<0.001a
2PN (%)69 (28)3,447 (33)551 (44)3,63174 (68)4,5,6<0.01a
Embryos resulting from 2PN 1‐cell zygotes (%)66 (96)734 (72)7,844 (86)93047 (95)8,9<0.01a
1PN (%)12 (5)8 (5)6 (5)233 (5)NSb
3PN (%)26 (10)109 (6)5 (4)186 (4)10<0.0001b
No. of blastomeres (mean ±  SD)3.3 ± 1.03.1±1.03.1 ± 1.13.4 ± 1.0NSc
Morphology score (mean ± SD)1.5 ± 0.71.5 ± 0.52.0 ± 1.01.9 ± 0.7NSc
aχ2 test; bFisher’s exact test; cone‐way ANOVA.
Comparisons were made between numbers denoted with the same superscript.



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