2012年12月30日

Day 2單一胚胎植入+多餘胚胎冷凍解凍植入之累積懷孕率與單一囊胚植入+多餘囊胚冷凍解凍植入之累積懷孕率相近 (34.2% versus 37.9%).

http://humrep.oxfordjournals.org/content/24/5/1051.full

Single Day 2 embryo versus blastocyst-stage transfer: a prospective study integrating fresh and frozen embryo transfers

Table III

Fresh cycles: clinical outcome in eSET and SBT groups

	eSET group	SBT group	P-value
Number of transfers (%)	243 (100)	218 (93)	<0.0001
Number of clinical pregnancies	71	92
Rate per transfer	29.2%	42.2%	<0.006
Rate per oocyte retrieval	29.2%	39.1%	<0.03
Number of gestational sacs	72	95
Clinical implantation rate	29.6%	43.6%	<0.004
Number of miscarriages (%)	7 (9.9)	7 (7.6)	NS
Number of ectopic pregnancies (%)	3 (4.2)	2 (2.2)	NS
Number of deliveries	61	80
Rate per transfer	25.1%	36.7%	<0.01
Rate per oocyte retrieval	25.1%	34.0%	<0.05
Number of multiple deliveries (%)	1 (1.6)	3 (3.8)	NS

Clinical implantation rate = Number of gestational sacs/Number of transferred embryos.

Table V

Cumulative clinical pregnancies and deliveries combining fresh and frozen–thawed cycles in eSET and SBT groups

		eSET group	SBT group	P-value
Number of couples		243	235
Number of clinical pregnancies	Fresh embryo transfer	71	92
	Frozen–thawed embryo transfer	26	9
	Overall results Rate per couple	97 (39.9%)	101 (43.0%)	NS
Number of cumulative multiple pregnancies (%)		4 (4.1)	3 (2.0)	NS
Number of deliveries	Fresh embryo transfer	61	80
	Frozen–thawed embryo transfer	22	9
	Overall results Rate per couple	83 (34.2%)	89 (37.9%)	NS
Number of cumulative multiple deliveries (%)		4 (4.8)	3 (3.4)	NS
Number of cycles	Fresh cycles	243	235
	Frozen–thawed cycles	143	76
	Total cycles	386	311
Mean number of cycles per delivery		4.65 (386/83)	3.49 (311/89)	<0.04

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