歐洲統計試管嬰兒懷孕率約30% 人工受孕懷孕率約12%

2005全歐洲統計
試管嬰兒懷孕率(每次植入)約30%
人工受孕懷孕率(<40y)約12%
人工受孕懷孕率(>40y)約12%

http://humrep.oxfordjournals.org/content/24/6/1267.full

Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE

ESHRE. The European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE)

1. A. Nyboe Andersen1, 
2. V. Goossens, 
3. S. Bhattacharya, 
4. A.P. Ferraretti,
5. M.S. Kupka, 
6. J. de Mouzon, 
7. K.G. Nygren and 
8. The European IVF-monitoring (EIM) Consortium, for the European Society of Human Reproduction and Embryology (ESHRE)†

+Author Affiliations

1. ESHRE Central Office, Meerstraat 60 B-1852, Grimbergen, Belgium

1. 1Correspondence address. The Fertility Clinic 4071, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. Tel: +45-35-45-13-15 or +45-35-45-49-76; Fax: +45-35-45-49-46; E-mail:anders.nyboe.andersen@rh.regionh.dk

• Received December 15, 2008.
• Revision received December 15, 2008.
• Accepted January 6, 2009.

 

Next Section

Abstract

BACKGROUND Results of assisted reproductive techniques from treatments initiated in Europe during 2005 are presented in this ninth report. Data were mainly collected from existing national registers.

METHODS From 30 countries, 923 clinics reported 418 111 treatment cycles including: IVF (118 074), ICSI (203 329), frozen embryo replacement (79 140), oocyte donation (ED, 11 475), preimplantation genetic diagnosis/screening (5846) and in vitro maturation (247). Overall, this represents a 13.6% increase since 2004, partly due to inclusion of 28 417 cycles from Turkey. European data on intrauterine insemination using husband/partner's semen (IUI-H) and donor semen (IUI-D) were reported from 21 countries and included 128 908 IUI-H and 20 568 IUI-D cycles.

RESULTS In 16 countries where all clinics reported to the IVF register, 1115 cycles were performed per million inhabitants. For IVF, the clinical pregnancy rates per aspiration and per transfer were 26.9% and 30.3%, respectively. For ICSI, the corresponding rates were 28.5% and 30.9%. After IUI-H, the clinical pregnancy rate was 12.6% per insemination in women <40. After IVF and ICSI, the distribution of transfer of one, two, three and four or more embryos was 20.0%, 56.1%, 21.5% and 2.3%, respectively. Huge differences exist between countries. The distribution of singleton, twin and triplet deliveries after IVF and ICSI was 78.2%, 21.0% and 0.8%, respectively. This gives a total multiple delivery rate of 21.8% compared with 22.7% in 2004 and 23.1% in 2003. In women <40 years of age, IUI-H was associated with a twin and triplet pregnancy rate of 11.0% and 1.1%, respectively.

CONCLUSIONS Compared with earlier years, there was an increase in the reported number of ART cycles in Europe. Although fewer embryos were transferred per treatment, there was a marginal increase in pregnancy rates and a reduction in multiple deliveries.

Table VI

Pregnancies and deliveries after IVF in 2005

Country	Cycles	Aspirations	Transfers	Clinical Pregnancies	Deliveries	Pregnancies per cycle (%)	Pregnancies per aspiration (%)	Pregnancies per transfer (%)	Deliveries per cycle (%)	Deliveries per aspiration (%)	Deliveries per transfer (%)
Albania	61	58	57	14	12	23.0	24.1	24.6	19.7	20.7	21.1
Belgium		3796	3417	914	713		24.1	26.7		18.8	20.9
Bulgaria	427	407	386	85	52	19.9	20.9	22.0	12.2	12.8	13.5
Croatia	1295	1255	1188	295	215	22.8	23.5	24.8	16.6	17.1	18.1
Czech Republic	1425	1255	1097	416	299	29.2	33.1	37.9	21.0	23.8	27.3
Denmark	5322	5104	4387	1409	890	26.5	27.6	32.1	16.7	17.4	20.3
Finland	2810	2736	2433	678	519	24.1	24.8	27.9	18.5	19.0	21.3
France	23 237	21 516	18 086	4969	3752	21.4	23.1	27.5	16.1	17.4	20.7
Germany	11 410	10 592	10 247	3116	1924	27.3	29.4	30.4	16.9	18.2	18.8
Greece	3178	3019	2789	969	693	30.5	32.1	34.7	21.8	23.0	24.8
Hungary	757	712	655	228	169	30.1	32.0	34.8	22.3	23.7	25.8
Iceland		182	151	64	49		35.2	42.4		26.9	32.5
Ireland	1429	1186	1099	349	301	24.4	29.4	31.8	21.1	25.4	27.4
Italy	8994	7675	6521	1724	717	19.2	22.5	26.4	8.0	9.3	11.0
Lithuania		25	25	5	4		20.0	20.0		16.0	16.0
Macedonia	328	310	246	97	67	29.6	31.3	39.4	20.4	21.6	27.2
Montenegro	18	18	17	6	4	33.3	33.3	35.3	22.2	22.2	23.5
Norway	2724	2605	2340	758	619	27.8	29.1	32.4	22.7	23.8	26.5
Poland	469	436	400	140	83	29.9	32.1	35.0	17.7	19.0	20.8
Portugal		1181	1042	369	279		31.2	35.4		23.6	26.8
Russia C.I.S.	9092	8715	8104	2865	1715	31.5	32.9	35.4	18.9	19.7	21.2
Serbia	21	10	6	3	3	14.3	30.0	50.0	14.3	30.0	50.0
Slovenia	730	694	584	199	163	27.3	28.7	34.1	22.3	23.5	27.9
Spain	4431	4209	3608	1292	437	29.2	30.7	35.8	9.9	10.4	12.1
Sweden	5033	4695	4273	1458	1154	29.0	31.1	34.1	22.9	24.6	27.0
Switzerland	722	648	579	165	125	22.9	25.5	28.5	17.3	19.3	21.6
The Netherlands	8896	8146	7048	1729		19.4	21.2	24.5	0.0	0.0	0.0
Turkey	707	561	532	249	68	35.2	44.4	46.8	9.6	12.1	12.8
Ukraine	1864	1815	1669	555	408	29.8	30.6	33.3	21.9	22.5	24.4
UK	17 510	15 208	13 743	4182	3698	23.9	27.5	30.4	21.1	24.3	26.9
All		108 769	96 729	29 302			26.9	30.3

Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE

Table XIII

IUI-H in 2005

Country	Cycles	Pregnancies	Pregnant (%)	Singleton	%	Twin	%	Triplet	%
Women <40 years
Albania	24	3	12.5	3	100.0	0	0.0	0	0.0
Belgium
Bulgaria	501	46	9.2	41	89.1	4	8.7	0	0.0
Croatia	1054	119	11.3	115	88.2	4	3.4	0	0.0
Czech Republic
Denmark	8223	1215	14.8	998	82.1	126	10.4	27	2.2
Finland	2572	317	12.3	216	68.1	12	3.8	1	0.3
France	51 375	5973	11.6	3957	66.2	487	8.2	23	0.4
Germany
Greece	1991	403	20.5	309	75.7	85	20.8	9	2.2
Hungary	1871	245	13.1	209	85.3	35	14.3	1	0.4
Iceland
Ireland	1194	110	9.2	94	85.5	8	7.3	0	0.0
Italy	21 116	2499	11.8	2210	88.4	258	10.3	24	1.0
Lithuania	156	12	7.7	11	91.7	1	8.3	0	0.0
Macedonia	555	59	10.6	45	76.3	14	23.7	0	0.0
Montenegro
Norway	498	58	11.6	43	74.1	5	8.6	0	0.0
Poland	3365	460	13.7	408	88.7	49	10.7	3	0.7
Portugal	1320	152	11.5	81	53.3	13	8.6	1	0.7
Russia C.I.S.	2634	470	17.8	429	91.3	37	7.9	4	0.9
Serbia	100	21	21.0	18	85.7	3	14.3		0.0
Slovenia	470	56	11.9	49	87.5	7	12.5	0	0.0
Spain	20 594	2783	13.5	2407	86.5	313	11.2	63	2.3
Sweden
Switzerland
The Netherlands
Turkey	167	33	19.8	26	78.8	7	21.2	0	0.0
Ukraine	833	120	14.4	118	98.3	2	1.7		0.0
UK
All	120 613	15 154	12.6	11 787	87.9	1470	11.0	156	1.1
Women >40 years
Albania	0	0		0		0		0
Belgium
Bulgaria	41	2	4.9	1	50.0	0	0.0	0	0.0
Croatia	161	13	8.1	13	100.0		0.0		0.0
Czech Republic
Denmark	619	47	7.6	41	87.2	1	2.1	0	0.0
Finland	161	8	5.0	6	75.0	0	0.0	0	0.0
France
Germany
Greece	581	56	9.6	50	89.3	6	10.7	0	0.0
Hungary	152	9	5.9	9	100.0	0	0.0	0	0.0
Iceland
Ireland	199	11	5.5	10	90.9	0	0.0	0	0.0
Italy	4309	237	5.5	229	96.6	8	3.4	0	0.0
Lithuania	6	0	0.0	0
Macedonia	31	2	6.5	2	100.0	0	0.0	0	0.0
Montenegro
Norway
Poland	291	21	7.2	20	95.2	1	4.8	0	0.0
Portugal	46	1	2.2	1	100.0	0	0.0	0	0.0
Russia C.I.S.	175	22	12.6	22	100.0	0	0.0	0	0.0
Serbia	18	4	22.2	4	100.0		0.0		0.0
Slovenia
Spain	1484	183	12.3	165	90.2	14	7.7	4	2.2
Sweden
Switzerland
The Netherlands
Turkey	5	1	20.0	1	100.0	0	0.0	0	0.0
Ukraine	16	0	0.0
UK
All	8295	617	7.4	574	94.4	30	4.9	4	0.7