子宮內膜緻密度（endometrial compaction, EC）定義為從卵泡期結束到胚胎移植（ET）之日的子宮內膜厚度差異

EC 在確定IVF著床率 方面的預測價值仍處爭議

=====================================================================

本篇研究顯示:  與沒有變化或增厚的女性相比，在 ET 當天子宮內膜緻密EC的女性的臨床懷孕率顯著更高。

Clinical pregnancy rates were significantly higher in women with endometrial compaction on ET day compared to women with no changes or thickening.  

https://link.springer.com/article/10.1007/s10815-023-02809-

=====================================================================

本篇研究顯示:  EC 在確定IVF著床率 方面的預測價值不高. 

J Assist Reprod Genet

. 2023 Nov;40(11):2513-2522.

 doi: 10.1007/s10815-023-02942-5. Epub 2023 Sep 20.

Can endometrial compaction predict live birth rates in assisted reproductive technology cycles? A systematic review and meta-analysis

Purpose: Endometrial compaction (EC) is defined as the difference in endometrial thickness from the end of the follicular phase to the day of embryo transfer (ET). We aimed to determine the role of EC in predicting assisted reproductive technology (ART) success by conducting a meta-analysis of studies reporting the association between EC and clinical outcomes of ART.Methods: MEDLINE via PubMed, Web of Science, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched from the date of inception to May 19, 2023. The primary outcome was live birth rate (LBR) per ET. Secondary outcomes were live birth or ongoing pregnancy per ET, ongoing pregnancy per ET, clinical pregnancy per ET, and miscarriage per clinical pregnancy.Results: Fifteen studies were included. When data from all studies reporting live birth were pooled, overall LBR rates were comparable in cycles showing EC or not [RR = 0.97, 95%CI = 0.92 to 1.02; 10 studies, 11,710 transfer cycles]. In a subgroup of studies that included euploid ET cycles, a similar LBR for patients with and without EC was noted [RR = 0.99, 95%CI = 0.86 to 1.13, 4 studies, 1172 cycles]. The miscarriage rate did not seem to be affected by the presence or absence of EC [RR = 1.06, 95%CI = 0.90 to 1.24; 12 studies].Conclusion: The predictive value of EC in determining LBR is limited, and assessment of EC may no longer be necessary, given these findings.

=====================================================================