2012年1月3日

檢測卵巢功能方法

檢測卵巢功能方法:

Age
Basal serum FSH    
Basal serum estradiol    
Basal LH/FSH ratio    
Basal serum inhibin-B level    
Basal serum anti-Müllerian hormone level    
Basal ovarian volume    
Basal antral follicle count    
Ovarian stromal blood flow    
Ovarian biopsy    

其中最廣泛使用為:
Day 3 FSH
Antral follicle
AMH (anti-Müllerian hormone)


卵巢功能檢測對年輕,卵巢功能正常之病患價值有限

對高齡,卵巢功能退化之病患具較高價值,可提供誘導排卵劑量及預估取卵數量之根據
卵巢功能檢測無法準確預估卵子品質



Assessment of ovarian reserve—should we perform tests of ovarian reserve routinely?

Table IV.
Summary of tests of ovarian reserve
TestGood screening testGood diagnostic testGood prognostic test
Basal serum FSHx?x
Basal serum antral follicle countx?x
Basal serum estradiolx?x
Basal serum anti-Müllerian hormone levelUnder evaluationUnder evaluationx
Basal serum inhibin-Bx?x
Ovarian volumex?x
Ovarian biopsyx?x
Ovarian stromal blood flowx?x
Clomiphene citrate challenge test (CCCT)x?x
GnRH agonist stimulation test (GAST)x?x
Exogenous FSH ovarian reserve test (EFORT)x?x


http://humrep.oxfordjournals.org/content/21/11/2729.full


Assessment of ovarian reserve—should we perform tests of ovarian reserve routinely?
  1. Siladitya Bhattacharya
+Author Affiliations
  1. Department of Obstetrics and Gynecology, Aberdeen University, Assisted Conception Unit, Aberdeen Maternity Hospital, Aberdeen, UK
  1. 1To whom correspondence should be addressed at: Department of Obstetrics and Gynecology, Aberdeen University, Assisted Conception Unit, Aberdeen Maternity Hospital, Aberdeen AB25 2ZL, UK. E-mail: abha.maheshwari@abdn.ac.uk

    Abstract

    Women undergoing IVF are routinely subjected to one or more tests of ovarian reserve. The results of these tests are also being extrapolated to women attending infertility clinics and those planning to delay childbearing. This debate examines the predictive power of currently available tests of ovarian reserve and questions the value of subjecting women to ovarian reserve tests. We propose that in the absence of an agreement on (i) a definition of poor ovarian reserve, (ii) the population to be tested and (iii) which interventions are effective in women with poor ovarian reserve, routine ovarian reserve testing is unhelpful.

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