Age
|
Basal serum FSH
|
Basal serum estradiol
|
Basal LH/FSH ratio
|
Basal serum inhibin-B level
|
Basal serum anti-Müllerian hormone
level
|
Basal ovarian volume
|
Basal antral follicle count
|
Ovarian stromal blood flow
|
Ovarian biopsy
|
其中最廣泛使用為:
Day 3 FSH
Antral follicle
AMH (anti-Müllerian hormone)
卵巢功能檢測對年輕,卵巢功能正常之病患價值有限
對高齡,卵巢功能退化之病患具較高價值,可提供誘導排卵劑量及預估取卵數量之根據
卵巢功能檢測無法準確預估卵子品質
Assessment of ovarian reserve—should we perform tests of ovarian reserve routinely?
Test | Good screening test | Good diagnostic test | Good prognostic test |
---|---|---|---|
Basal serum FSH | x | ? | x |
Basal serum antral follicle count | x | ? | x |
Basal serum estradiol | x | ? | x |
Basal serum anti-Müllerian hormone level | Under evaluation | Under evaluation | x |
Basal serum inhibin-B | x | ? | x |
Ovarian volume | x | ? | x |
Ovarian biopsy | x | ? | x |
Ovarian stromal blood flow | x | ? | x |
Clomiphene citrate challenge test (CCCT) | x | ? | x |
GnRH agonist stimulation test (GAST) | x | ? | x |
Exogenous FSH ovarian reserve test (EFORT) | x | ? | x |
http://humrep.oxfordjournals.org/content/21/11/2729.full
Assessment of ovarian reserve—should we perform tests of ovarian reserve routinely?
+Author Affiliations
- 1To whom correspondence should be addressed at: Department of Obstetrics and Gynecology, Aberdeen University, Assisted Conception Unit, Aberdeen Maternity Hospital, Aberdeen AB25 2ZL, UK. E-mail: abha.maheshwari@abdn.ac.uk
Abstract
Women undergoing IVF are routinely subjected to one or more tests of ovarian reserve. The results of these tests are also being extrapolated to women attending infertility clinics and those planning to delay childbearing. This debate examines the predictive power of currently available tests of ovarian reserve and questions the value of subjecting women to ovarian reserve tests. We propose that in the absence of an agreement on (i) a definition of poor ovarian reserve, (ii) the population to be tested and (iii) which interventions are effective in women with poor ovarian reserve, routine ovarian reserve testing is unhelpful.
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