雷射後精蟲顯微注射有助改善胚胎品質

 

雷射打薄中空透明帶(ZP)後精蟲顯微注射可能有助改善D2或 D3胚胎品質
但對胚胎懷孕率或著床率無明顯提升

http://humrep.oxfordjournals.org/content/17/5/1317.full





Laser‐assisted zona pellucida thinning prior to routine ICSI

Table I.

Comparison of preimplantation development in vitro between laser‐assisted ICSI and conventional ICSI

	Laser‐assisted ICSI	Conventional ICSI
Number of MII oocytes	514	502
Fertilization (2PN)	350 (68.1)	332 (66.1)
No fertilization	114 (22.2)	98 (19.5)
1 PN	6 (1.2)	3 (0.6)
3 PN	13 (2.5)	13 (2.6)
Degeneration	31 (6.0)a	56 (11.2)a
No or minor fragmentation on day 2	237/360 (65.8)a	192/348 (55.2)a
No or minor fragmentation on day 3	206/360 (57.2)	178/348 (51.2)
Day 4 compaction	142/235 (60.4)	120/229 (52.4)
Day 5 number of blastocysts	111/235 (47.2)	102/229 (44.5)
Good quality blastocysts	34/81 (42.0)	33/82 (40.2)
Hatching blastocysts	27/111 (24.3)b	10/102 (9.8)b